摘要 :
The antihypoxic activities of new benzothiazole derivatives were studied in experiments on outbred male mice. The effects were found to be directly determined not only by the type of substituent on the heterocycle but also the org...
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The antihypoxic activities of new benzothiazole derivatives were studied in experiments on outbred male mice. The effects were found to be directly determined not only by the type of substituent on the heterocycle but also the organic acid in the molecule. The most pronounced effect was observed for molecules containing a succinate fragment.
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摘要 :
<abstract_text><p>New 2-amino-6-ethoxybenzothiazole derivatives were synthesized and tested for their influence on physical work capacity in mice. It was shown that a pyridylidene or furylidene radical on the amine or a formulatio...
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<abstract_text><p>New 2-amino-6-ethoxybenzothiazole derivatives were synthesized and tested for their influence on physical work capacity in mice. It was shown that a pyridylidene or furylidene radical on the amine or a formulation with carboxypentanoate were important for producing effective new 2-amino-6-ethoxybenzothiazole derivatives. These compounds were either more effective or comparable with the well-known actoprotectors metaprot and ladasten, which are used at significantly higher doses.</p></abstract_text>
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